The Trimmer Lab was active from 1990-2024. During this time we investigated the expression, localization, function, and modulation of ion channel signaling complexes that underlie the compartmentalized function of discrete subcellular domains in neurons. Related efforts continue in the labs of former trainees and collaborators.

From 1990-2024 we generated, validated, and used renewable affinity reagents to label, capture, and/or influence activity of specific targets in brain neurons, and to use as intrabodies to deliver cargo to specific subcellular locations.  These efforts continue at the UC Davis/NIH NeuroMab Facility (https://neuromab.ucdavis.edu/)